Mikel Arteta is expected to make a number of changes to the team which beat Molde 3-0 in midweek as Arsenal prepare to host Wolves on Sunday night.
The Emirates clash is expected to come too soon for Bukayo Saka but Willian has a chance of making the starting XI after both stars were injured during last weekend’s 0-0 draw at Leeds.
Elsewhere, the Gunners will be without suspended winger Nicolas Pepe, while midfielder Thomas Partey and defender David Luiz are serious doubts.
A number of Arsenal’s youngsters impressed in the Europa League win on Thursday, but Arteta is expected to call on his seasoned performers for the testing visit of Wolves.
As such, Arsenal will likely line up with a back five ahead of goalkeeper Bernd Leno, with Rob Holding, Gabriel and Kieran Tierney fielded at centre-back.
Hector Bellerin and Ainsley Maitland-Niles may be called on in the wing-back roles, with the latter filling in for Saka as the 19-year-old continues his recovery from a knee injury.
“It’s very doubtful [that Saka will be back in time for Wolves],” Arteta said on Wednesday.
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“He’s been in a lot of pain for the last few days so I cannot say today that he’s going to be fit.”
In midfield, Granit Xhaka and Dani Ceballos are expected to get the nod after their industrious displays at Elland Road last weekend.
But there may be a shake-up in attack that sees Pierre-Emerick Aubameyang return to the left flank after he was fielded as a centre-forward against Leeds.
This would allow Alexandre Lacazette to return to the forward trio and Willian to line up on the right wing, should he overcome his calf issue.
Discussing the Brazilian, Arteta said: “He has not travelled to Molde. He will continue to be assessed and aiming to be available for Sunday’s match against Wolves.”
Arsenal predicted starting XI: Leno; Bellerin, Holding, Gabriel, Tierney, Maitland-Niles; Ceballos, Xhaka; Willian, Lacazette, Aubameyang.