Bloemfontein Celtic goalkeeper Mabokgwane in fitness race ahead Orlando Pirates clash

Bloemfontein Celtic coach John Maduka is fretting over the fitness of goalkeeper Jackson Mabokgwane and midfielder Lantshene Phalane, ahead of meeting Orlando Pirates in Wednesday’s Premier Soccer League (PSL) match at Dr Petrus Molemela Stadium.

Mabokgwane might not face his former club after lasting 66 minutes in Sunday’s 1-1 MTN8 semi-final, first leg draw away at SuperSport United on Sunday.

It was a double injury blow after Phalane played just 28 minutes of the match and before being taken off complaining of pain on his groin.

“I have not met the medical team yet and I am not sure of [Phalane’s] situation. I just heard that Jackson has been taken to hospital but Phalane is still with the team‚” said Maduka as per Sowetan Live.

“I have not gotten the [medical] reports yet to see how bad the injuries are. Yeah we will first check you know if there might be some few knocks here and there.

“It is very important for us to introduce the fresh legs. We have been playing every three days‚ so it is very important to go to the game against Pirates also refreshed a little bit.

“There might be some changes‚ one or two or three so that the team can be able to compete on Wednesday [against Pirates].”

Given Mashinkinya came on for Phalane on Sunday and could step in again if the midfielder fails to recover in time for the Pirates match.

A 1-1 draw against Golden Arrows and a 1-0 defeat by Swallows FC characterise Celtic’s PSL campaign so far.

Celtic host the Buccaneers who arrive in Bloemfontein on a high after convincingly beating Kaizer Chiefs 3-0 in the MTN8 semi-final, first leg match on Saturday.

Pirates are expecting forward Frank Mhango to be back after the Malawi forward missed the Chiefs match due to injury.

They will be without coach Josef Zinnbauer who has been granted leave to travel back to Germany to attend to his hospitalised son.

The Soweto giants are yet to win a league match after drawing their two matches games against AmaZulu and Stellenbosch on 1-1 scorelines.

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Race Against Time for Boy Battling Rare, Alzheimer’s-like Illness | Health News

By Dennis Thompson HealthDay Reporter


MONDAY, Nov. 2, 2020 (HealthDay News) — Connor Dobbyn is an energetic and loving 12-year-old, but he’s fading away every second.

Connor has Sanfilippo syndrome, a genetic brain disorder in children that experts compare to Alzheimer’s disease.

The boy already has lost some of what he’s learned in his short time on Earth, and every day he loses a little more.

“We’re on borrowed time. They don’t live through their teens,” said his mom, Marisa DiChiacchio, who lives with Connor in West Chester, Pa. “We have six years left, at most.”

Here’s the good news: Researchers think they’ve found a cure for Connor’s type of Sanfilippo, a therapy that replaces the bad gene in his body with a healthy working version.

But they need millions of dollars in funding to test this potential cure. Connor’s parents have set up a GoFundMe page with a goal of $3 million for a clinical trial that could save their son’s life.

“The research is done. It’s like right there, but they need the money to fund the clinical trial,” DiChiacchio explained.

Kids with Sanfilippo syndrome suffer from the build-up of a long-chain sugar molecule called heparan sulfate, which is normally used by the body to build cartilage, connective tissues, nerve tissues and skin, according to the Nemours Foundation.

These kids have a defect in one of the genes that make enzymes needed to break down heparan sulfate. Without those enzymes, heparan sulfate “builds up everywhere in the body and the brain,” explained Cara O’Neill, chief science officer and co-founder of the Cure Sanfilippo Foundation.

As the substance clogs the brain and body, kids begin experiencing the sort of mental and physical decline associated with dementia in seniors. Kids lose knowledge and skills they’ve gained, develop seizures, experience hearing and vision loss, find it difficult to walk and move, and even struggle to chew and swallow food, O’Neill said.

“These kids become nonverbal. They lose their ability to walk and talk. They’re in wheelchairs and in strollers. Almost all of them develop seizures and different movement disorders,” DiChiacchio said. “There’s literally no cure at this point. These kids are dying.”

Sanfilippo syndrome is relatively rare, occurring in about 1 out of every 70,000 children, O’Neill said.

“We think it’s underdiagnosed because it’s usually masked as autism,” said Glenn O’Neill, president and co-founder of the Cure Sanfilippo Foundation. “Kids exhibit the typical symptoms of autism early in life while parents are trying to figure out what’s going on. But then things actually begin actually going backwards, in the wrong direction.”

That’s what happened with Connor. He’d been struggling with developmental delays since he was 1 year old, and at age 5 he received a diagnosis of autism, DiChiacchio said.

But during a psychological evaluation in the third grade, educators were stunned to find a drastic decline in Connor’s IQ, his mom said.

“It was like a bomb went off,” DiChiacchio said. “His average IQ in kindergarten was 100, and

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NSW fullback dilemma intensifies as Papenhuyzen joins Tedesco in Origin fitness race

Papenhuyzen, as well as Storm teammates Dale Finucane and Josh Addo-Carr, arrived at NSW’s Central Coast camp on Wednesday afternoon to undergo a series of medical examinations on the calf strain.

Melbourne’s grand final celebrations since Sunday night wouldn’t have provided Papenhuyzen much time to treat the injury, while the consumption of alcohol would have only hampered his recovery.

Blues teammates Jack Wighton, Clint Gutherson and Nathan Cleary watch on during last week's Dally M Medal ceremony.

Blues teammates Jack Wighton, Clint Gutherson and Nathan Cleary watch on during last week’s Dally M Medal ceremony.Credit:Grant Trouville/NRL Photos

Gutherson has predominantly been training at fullback for the Blues during training with Tedesco on restricted duties. The Roosters fullback has given himself until Saturday to make a decision.

The Blues are on Thursday expected to announce a 21-man squad for game one at Adelaide Oval next Wednesday, with Fittler still uncertain on the make-up of his best 17.

The fullback conundrum will go a long way to determining the back line, given Fittler had earmarked Gutherson to partner Jack Wighton in the centres, but the uncertainty around his first-choice fullbacks could see him bring in another debutant.

If Gutherson moves to fullback, St George Illawarra’s Zac Lomax and Penrith’s Stephen Crichton will do battle for the centre position expected to be vacated by the Eels captain’s shift.

Working in Lomax’s favour is the fact he is a specialist right centre, however he hasn’t played since the first weekend of September when the Dragons bowed out of the competition. Crichton is a left centre, however he has the added advantage of being in peak condition given the Panthers only finished up a few days ago after the grand final loss to Melbourne at ANZ Stadium.

The Blues are confident five-eighth Luke Keary will be fit to play despite adding Jarome Luai to the squad as extra cover at five-eighth on top of the inclusion of Walker.


Fittler also has to decide between Canberra’s Nick Cotric and the Roosters’ Daniel Tupou for the right wing spot. The front row rotation was also a topic of conversation at the Blues’ selection meeting on Wednesday with one of Junior Paulo, Payne Haas, Daniel Saifiti and Reagan Campbell-Gillard a chance of being left out of the side.

Queensland are expected to blood up to nine debutants for the opening game of the series, including AJ Brimson, Xavier Coates, Brenko Lee, Tino Faasuamaleaui, Mosese Fotuaika, Lindsay Collins, Jake Friend, Jaydn Su’A and Kurt Capewell.

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Shanghai’s Zeng faces fitness race after finger injury

HONG KONG (Reuters) – Veteran goalkeeper Zeng Cheng faces a race against time to be ready for Shanghai Shenhua’s opening fixture in the rescheduled 2020 Asian Champions League group phase next month after breaking the little finger on his right hand.

The 33-year-old, who joined Shenhua on loan from Guangzhou Evergrande ahead of the current season, is expected to be sidelined for at least three weeks after damaging his finger, according to a Shenhua club official.

That means Zeng, who won the Asian title with Guangzhou in 2013 and 2015, is a doubt for his club’s opening fixture of the competition in Doha against Australian side Perth Glory on Nov. 18.

Zeng is one of the most successful players in the history of Chinese football, having won the Chinese Super League title with Guangzhou on six occasions between 2012 and 2019. He has also represented China 42 times.

The group phase of the Asian Champions League featuring clubs from the east of the continent was due to be held from February until May but was postponed due to the coronavirus pandemic.

It is now being played in the Qatari capital from Nov. 18 until Dec. 13 with the final, against already-qualified Persepolis of Iran, also in Doha on Dec. 19.

Reporting by Michael Church, Editing by Clare Fallon

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Surging coronavirus colors White House race in closing days

WAUKESHA, Wis. (AP) — President Donald Trump assured supporters packed shoulder to shoulder at weekend rallies that “we’re rounding the turn” on the coronavirus and mocked challenger Joe Biden for raising alarms about the pandemic, despite surging cases around the country and more positive infections at the White House.

Trump’s remarks came Saturday, hours before the White House announced that a top aide to Vice President Mike Pence had tested positive for the virus. Pence has been in close contact with the adviser, the White House said, but still planned to keep traveling and holding rallies around the country.

The revelation of another high-ranking administration official testing positive for the virus coupled with the administration’s decision to continue business as usual punctuated a day that marked the starkly different approaches that Trump and Biden are taking to campaigning in the age of the novel coronavirus.

Pence’s office confirmed late Saturday that his chief of staff, Marc Short, had tested positive — the public announcement coming just as Trump was wrapping up a day of big rallies in North Carolina, Ohio and Wisconsin, three battleground states that will have enormous impact on deciding the Nov. 3 election.

Trump commented on Short early Sunday after his plane landed at Joint Base Andrews, outside Washington. “I did hear about it just now,” he said. “And I think he’s quarantining. Yeah. I did hear about it. He’s going to be fine. But he’s quarantining.”

Pence is considered a “close contact” under Centers for Disease Control and Prevention guidelines, but will continue to campaign, his spokesman said. “In consultation with the White House Medical Unit, the Vice President will maintain his schedule in accordance with the CDC guidelines for essential personnel,” Pence spokesman Devin O’Malley said. The guidelines require that essential workers exposed to someone with the coronavirus closely monitor for symptoms of COVID-19 and wear a mask whenever around other people.

O’Malley added that Pence and his wife, Karen Pence, both tested negative for the virus on Saturday “and remain in good health.” Pence, who held campaign events in Florida on Saturday, is set to campaign in North Carolina on Sunday.

The revelation bookended a day in which Biden and Trump demonstrated remarkably different attitudes about what they saw as safe behavior in the homestretch of a campaign that, as with all aspects of American life, has been upended by the pandemic.

“We don’t want to become superspreaders,” Biden told supporters at a “drive-in” rally Saturday in Bucks County, Pennsylvania, picking up a term that has been used to describe the Rose Garden event in late September in which Trump announced his latest Supreme Court nominee. More than two dozen people linked to the White House have contracted COVID-19 since that gathering, as have campaign aides. Trump spent more than three days hospitalized at Walter Reed Military Medical Center after becoming stricken.

Biden pressed his case that Trump was showing dangerous indifference to the surging virus on a day he looked to boost his

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Worsening opioid crisis overshadowed in presidential race

COLUMBUS, Ohio (AP) — Like millions of Americans, Diane Urban watched the first presidential debate last month at home with her family. When it was over, she turned off the television and climbed into the bed her 25-year-old son Jordan used to sleep in.

It was where she found Jordan’s lifeless body after he overdosed on the opioid fentanyl one morning in April 2019.

After watching President Donald Trump target the son of former Vice President Joe Biden for his history of substance abuse, Urban was reminded again of the shame her son lived with during his own battle with addiction.

“I just think that Trump doesn’t understand addiction,” said Urban, 53, a Republican from Delphos, Ohio, who voted for the president in 2016.

The exchange over Hunter Biden’s struggle with addiction was brief, and neither candidate was asked a follow-up question about their plan to tackle the nation’s drug addiction and overdose crisis.

Though Biden’s campaign has a policy paper on addiction, the issue has barely registered in this year’s presidential campaign, overshadowed by the human and economic toll of the coronavirus outbreak and the Trump administration’s response to the pandemic. Yet drug addiction continues its grim march across the U.S., having contributed to the deaths of more than 470,000 Americans over the past two decades.

And it’s only getting worse.

After a one-year drop in 2018, U.S. opioid overdose deaths increased again in 2019, topping 50,000 for the first time, according to provisional data from the U.S. Centers for Disease Control and Prevention. That accounted for the majority of the 71,000 fatal overdoses from all drugs. While national data isn’t available for most of 2020, The Associated Press surveyed individual states that are reporting overdoses and found more drug-related deaths amid the coronavirus pandemic.

Ohio, a battleground state in the presidential contest, is on track to have one of its deadliest years of opioid drug overdoses. More residents died of overdoses in May than in any month in at least 14 years, according to preliminary mortality statistics from the state health department.

As Trump nears the end of his first term, some supporters, including Urban, feel left behind by his administration’s drug policies.

During Trump’s first two years in office, 48 of the 59 Ohio counties with reliable data saw their overdose death rates get worse, according to an analysis of CDC data by The Associated Press. The data was compared to overdose death rates in 2015 and 2016, the last two years of the Obama administration.

What that looks like on the ground is mothers donating to GoFundMe accounts and Facebook campaigns so other mothers can bury their children who’ve overdosed. Some parents even reserve a casket while their child is still alive so they are prepared for what they believe is inevitable.

Others become legal guardians of their grandchildren. Among them are Brenda Stewart, 62, and her husband, who adopted their grandchildren a decade ago as their son struggled with addiction. That led Stewart to start

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In the race for a COVID-19 vaccine, how do we balance risk and safety?

The great race for a COVID-19 vaccine has more than 130 medicines in development, with 40 being tested on humans, of which 10 are in large, phase 3 trials. The U.S. Government has invested about $11 billion in Operation Warp Speed, making advance purchases from Moderna, Johnson & Johnson, Pfizer/BioNTech, Sanofi/GlaxoSmithKline, Novavax and AstraZeneca — betting that at least some will be soon approved by regulators as “safe and effective” vaccines.

No matter your Twitter feed, “vaccines have been one of the greatest public health tools to prevent disease,” as The New York Times explained in January. But as late as May 9, the Times reported that “American officials and pharmaceutical executives have said that a (COVID-19) vaccine remains at least 12 to 18 months away.”

That forecast may prove unduly pessimistic: Good Judgment, a respected forecasting firm, places odds of a vaccine (approved and distributed to at least 25 million Americans by March 31, 2021), at 46%.

(And on Friday, Pfizer said it would not apply for emergency authorization of its vaccine before mid-November.)

Too fast? Many are terrified that the Food and Drug Administration may hastily authorize injections into hundreds of millions. The FDA and drugmakers are trying to assuage such concerns with enhanced commitments to safety. Nonetheless, fears have been stoked by President Donald Trump’s infomercial-style endorsement of hydroxychloroquine as a COVID-19 remedy, his foolhardy disdain for face masks and campaign rally boasts of a preelection cure.

Yes, politics. But the opposing political push — the demand that new vaccines must be safe at all costs — is itself a dangerous meme, and the strange bedfellow of anti-vaxxer protesters.

Pulitzer Prize-winning journalist Laurie Garrett inadvertently quantifies the problem. In a Sept. 3 article in Foreign Policy, she cited the H1N1 (swine flu) episode in 2009 as “the last mad rush to vaccinate.” Warning that those shots “caused Guillain-Barr (GBS) paralysis in … 6.2 per 10 million patients who received the vaccine,” she argues that phase 3 trials for COVID-19 vaccines, typically involving just 30,000 people, provide little protection. “There’s no way … we can spot a safety hazard that’s in 1 out of a million, much less 1 out of 10 million, vaccine recipients.” The “safety side,” she told a TV interviewer, “looks insane.”

But, in fact, the “insanity” here is not found in the push for speed or in Garrett’s skepticism about Operation Warp Speed. It lies in a lack of balance between the two. An insufficiently vetted vaccine may cost innocent lives, but so will delaying a vaccine that, on net, saves them.

COVID-19 now costs over 700 lives a day in the U.S. — 30 per hour. Would reducing the toll even by just one-third compensate for the possibility that as many as 205 people might be paralyzed (if every Americans were vaccinated and GBS spread at 6.2 per 10 million)? Presumably, yes — in less than a day.

Insane to move forward rapidly — or insane not to?

Indeed, the 2009

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Local dentist, activist Dr. Elenora Woods enters 2021 Chattanooga mayoral race

Dentist and activist Dr. Elenora Woods entered the 2021 race for mayor of Chattanooga Monday, promising opportunity, criminal justice reform and comprehensive homeless services if elected.

Woods, a single mother of three raised in the housing developments of the Westside of Chattanooga, said her rise to a successful career as a dentist and community activist have primed her for the role.

“I was born a little project girl on the Westside. And you know my favorite saying is, ‘it’s not where you come from, it’s where you’re going and how you get there,’ right? So one of the things that we’re going to continue to do is to make sure that we have opportunities for those who just need a hand up.

“I’m worried about your job and your community. I’m worried about the small business people that are struggling every day because they can’t pay this or can’t pay that. They’re taking from here, putting it over there,” she said. “The small business person runs this city, and that’s who I’m going to advocate for because I’m a small businesswoman myself and I understand what you go through every single day.”

Woods says she’s answering the call of community members who asked her to run with a promise of fighting to provide assistance for those in need.

“I’m sick and tired of seeing the statistics in education where Black and brown children are at the bottom of the list all the time. I’m sick and tired of that. I’m sick and tired of seeing homeless people on the streets of the city of Chattanooga, and everybody’s just walking over them like it’s OK. I’m sick and tired of all of the discrimination that goes on in our communities,” she added, also mentioning discrimination against women and poor communities.

To address these inequities, Woods said she will establish a veterans service office, invest in early childhood development, create a trade school and similar opportunities in the city and will invest in diverse and low-income neighborhoods to ensure equity in the city budget.

Woods said she would also “reorganize” the police department, up to potentially replacing the current police chief, and would incentivize the recruitment of Black officers.

Woods, who has led peaceful racial justice protests and served as president of Chattanooga’s NAACP chapter, said she would not defund the police but would seek a charter amendment to ban chokeholds.

“What we’re going to do is reorganize the police department and get rid of bad cops. And if that means a police chief, then we may start a new search, then so be it. So be it,” she said. “But we need police officers, we need them to protect you if something happens in your house. Who you gonna call? Ghostbusters?”

Asked about her ouster from the NAACP last year, Woods said she was limited on what she could say on the advice of her attorney.

“But like I said, it’s a wonderful organization. It’s the oldest and largest civil rights

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