Carrot-based Japanese herbal medicine may improve muscle complications associated with COPD

Chronic obstructive pulmonary disease (COPD) is a lung disease caused by long-term inhalation of harmful gases such as cigarette smoke. Scientists have recognized deterioration of muscle tissue, known as, as a secondary effect of damaged lungs. This frailty makes it difficult for individuals to move around and exercise, which is turn worsens the state of their lungs, causing an endless downward spiral in overall health.

Exercise therapy is the only established treatment for the skeletal muscle complications of COPD, however, depending on the severity of sarcopenia frailty in the patient, such treatment may not be possible. This imbalance has become an urgent issue to address. Ninjin’yoeito is a carrot-based Japanese herbal medicine commonly given to people recovering from anorexia and physical weakness after illness or surgery for its supplementary effect in restoring physical strength. Also, the medicine has been seen to improve muscle mass loss in aging mice through the activation of PGC-1α- a protein involved in improving muscle function.

Based on this, we hypothesized that Ninjin’yoeito enhances PGC-1α expression in skeletal muscle and may improve muscle complications associated with COPD.”

Kazuhisa Asai, Associate Professor, Osaka City University Graduate School of Medicine

He led a research group in testing this hypothesis by including Ninjin’yoeito in the diet of mice who had been exposed to cigarette smoke for 12 weeks. Their findings were published online in the international scientific journal International Journal of Chronic Obstructive Pulmonary Disease on November 27, 2020.

Professor Asai’s team measured the lower leg muscle mass of the smoke-exposed group of mice with a microCT and noticed they had atrophied, like human COPD patients. However, he saw no such change in muscle mass with the experimental group of mice, suggesting that the addition of the carrot-rich medicine cancels out the effects of sarcopenia frailty.

“We believe that this is a useful finding and that Ninjin’yoeito may break the vicious circle of sarcopenia frailty in COPD patients”, adds Associate Professor Asai. “We would like to consider clinical trials in the future.”


Journal reference:

Miyamoto, A., et al. (2020) Ninjin’yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression. International Journal of Chronic Obstructive Pulmonary Disease. doi.org/10.2147/COPD.S280401.

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NE China to open herbal medicine industrial park

(MENAFN) Northeast China’s Heilongjiang Province has exported an industrial park processing herbal medicines imported from Russia.

According to local officials, the industrial park in the Suifenhe sub-area of the Heilongjiang Pilot Free Trade Zone (FTZ) has seen the registration of six herbal medicine processing companies.

The park will have an annual medicine processing capacity of 165,000 tonnes, with an overall investment of 339 million yuan (about 51.46 million U.S. dollars),

A new policy allows herbal medicines, such as ginseng and licorice, from Russia to be processed in the Suifenhe area of the FTZ.

Imported drugs can be unloaded, primarily processed and sold directly in Suifenhe, thus helping companies reduce costs, said Wang Tengli, general manager of a local pharmaceutical trading company with an annual processing capacity of 2,000 tonnes.


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Medical groups clash over insurance coverage of herbal medicine

By Lee Hyo-jin

A pilot program rolled out by the government to include several types of herbal medicine in treatments covered by national health insurance was welcomed by practitioners of traditional Korean medicine. It, however, immediately provoked backlash from Western medical doctors.

As the government has plans to expand the coverage for more herbal medicine in the future following the progress of the trial program, the mixed reactions of the two medical groups may deepen into another dispute.

Under the pilot program, which started on Nov. 20, patients at traditional Korean medicine clinics who are prescribed treatments for menstrual pain, facial paralysis, or the aftereffects of cerebrovascular diseases, pay only half of the fee for the herbal medicine, as the rest is covered by state insurance.

The three-year test run is aimed at reducing the financial burden of patients and establishing a verified system to ensure the safety and effectiveness of herbal medicine, according to the Ministry of Health and Welfare.

Around 8,700 clinics providing traditional Korean medicine treatments across the country ― approximately 62 percent of the total ― have agreed to participate in the program.

Why Western medical doctors oppose

The announcement was immediately met with strong backlash from the Korea Medical Association (KMA), the largest Western medical doctors’ group in the country with more than 130,000 members. The association strongly condemned the government’s decision through a press release, calling it a “nationwide clinical trial using unverified medicine.”

They argued that easing public access to traditional Korean medicine and related herbal therapy will pose a risk to people’s health as they claim the safety of the treatments have not been adequately verified and there is no scientific evidence for their efficacy.

The association also pointed out that the program may lead to poor quality of herbal medicine, due to a shortage of certified herbal medication dispensaries and lenient control over them. While most small traditional Korean medicine clinics have own dispensaries, some large ones have outside dispensaries make the medicine.

“There are only five outside herbal medication dispensaries in the country certified by the government. This means that those five facilities will be preparing all the herbal medicines for over 8,700 clinics during the pilot program period,” KMA member Kim Gyo-woong said at a press conference, Nov. 23.

“The mass production system may lead to failure in quality control and safety issues, and considering the current lax control over dispensaries, the system may lead to illicit manufacturing of drugs,” he added.

In addition, the KMA stressed that the health authorities should focus more on the unresolved issues surrounding the side effects of traditional medicine.

More than half of medical disputes reported in relation to traditional medicine treatments were about herbal medicine, followed by Chuna manual therapy, acupuncture, and skin care, the association said, citing recent data from the Korea Consumer Agency.

“The government must immediately retract the policy which only puts public safety at risk, and launch a full investigation on all herbal dispensaries and prohibit the operation

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A review of Traditional Chinese herbal medicine in management of COVID-19

The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 59.65 million people worldwide and claimed the lives of over 1.4 million. The virus, first detected in late December 2019 in Wuhan, China, is the most significant public health problem since the 1918 Spanish flu pandemic. There are no effective and safe drugs that can be used to treat COVID-19 disease nor vaccine to prevent SARS-CoV-2 infection. Since the first cases were detected in Wuhan, several traditional Chinese herbal medicines have been used to treat this infection.

Now researchers led by David Lee from Bio-Organic and Natural Research Laboratory, McLean Hospital, Harvard Medical School, Belmont have summarized the experiences with the use of traditional Chinese herbal medicines for the management of COVID-19. Their study titled, “Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis,” was published in the January 2021 issue of the journal Phytomedicine.

Study: Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis. Image Credit: Dragon Images / Shutterstock


China has a rich history of traditional herbal medicines. Traditional Chinese herbal medicine (TCM) has been used for over 5,000 in over 300 epidemics that the nation has faced. When the COVID-19 pandemic emerged early this year, treatment with TCM was reported to have been used with over 90 percent efficacy.

Study particulars

This study was a systematic review of several traditional Chinese herbal medicines that were used in Wuhan,  looking at their efficacy in the management of COVID-19. At present, patients admitted to hospitals (except TCM hospitals) are primarily treated with western medicine as frontline treatment.

Principles of TCM use

The western medications used include antibiotics and painkillers. At present, over 100 herbal TCM formulae are available for use in epidemic related infections. Authors write, “TCM is now credited for the successful battle against COVID-19 in China”.

The ancient Chinese medical text Huangdi Neijing explains that 12 meridian lines run through the human body and help balance the immune system and provide good health. The lung meridian line interconnects with the large intestine functionally and controls the body fluid (water). The researchers write, “Expelling phlegm and relaxing the bowels with laxatives are common methods for treating lung diseases. Therefore, maintaining a smooth and open channel is an important function served by the lung meridian line.” Treatment of COVID-19 is basically to “expel the toxic moisture from the upper respiratory system and to improve intestinal obstruction.” They added that the TCM method of treatment tries to maintain the balance of the lung meridian system and to restore the lung and large intestine balance using acupuncture and herbal medicine.

Treatment of COVID-19 using TCM

TCM has been used as a first-line treatment for COVID-19 disease since the emergence of SARS-CoV-2. Qingfei Paidu decoction for example, has been used in a three-day course leading to an over 90 percent efficacy.

The team of researchers wrote, “The Chinese government announced that TCM is one of the recommended therapeutic options for the treatment of COVID-19 in the third version COVID-19 treatment guidelines, published on January

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Chinese herbal medicine launched in Philippines

Chinese herbal medicine launched in Philippines

Sheila Crisostomo (The Philippine Star) – November 25, 2020 – 12:00am

MANILA, Philippines — A Chinese herbal medicine designed to relieve influenza symptoms such as those of COVID-19 was officially launched in the Philippines on Monday.

According to Philippine Archipelago International Trading Corp. (PAITC) president Olivia Limpe-Aw, the Lianhua Qingwen capsule is the first traditional Chinese medicine registered by the Food and Drug Administration (FDA) under the “pharmacological category.”

“This a landmark registration? The COVID-19 pandemic has brought to fore the importance of TCM (traditional Chinese medicine) and, in particular, the significant role of Lianhua Qingwen in the treatment of COVID-19,” she noted in a webinar.

Aw added the medicine is now available at selected drugstores in the Philippines, but it will be accessible at more outlets soon.

She said the entry of Lianhua Qingwen in the country “will be a big help to our countrymen.”

AIf thereIs a silver lining to this COVID-19 pandemic, itss the awareness for traditional Chinese medicine and the provision for effective, safe and affordable treatment,s she maintained.


In August, the Chinese embassy in the Philippines had announced that the FDA had approved the application for registration of Lianhua Qingwen as a “traditional medicine.”

An embassy statement showed the product is manufactured by “one of China’s renowned Traditional Chinese Medicine manufacturers, Shijiazhuang Yiling Pharmaceutical Co. Ltd.”

In China, the Lianhua Qingwen capsule is an approved treatment for mild and moderate cases of COVID-19.

Based on Lianhua Qingwen’s certificate for product registration (CPR) issued by the FDA, the medicine “helps remove heat-toxin invasion of the lungs, including symptoms such as fever, aversion to cold, muscle soreness, stuffy and runny nose.”

The product can be procured in the Philippines with a doctor’s prescription.

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Herbal Medicine Market Size 2020 Trends, Research, Development Status, Opportunities, Plans, Competitive Landscape and Growth by Forecast 2026

The MarketWatch News Department was not involved in the creation of this content.

Nov 21, 2020 (The Expresswire) —
“Final Report will add the analysis of the impact of COVID-19 on this industry.”

Global “Herbal Medicine Market” report 2020 gives complete research on market size in the form of value, capacity, production and consumption in key regions like North America, Europe, Asia Pacific (China, Japan) and other regions. Players, stakeholders, and other participants in the global Herbal Medicine market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on Herbal Medicine industry revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2015-2026.

Get Sample Copy of this Report at: https://www.industryresearch.co/enquiry/request-sample/16690445

Herbal Medicine Market Summary: Herbal medicine–also called botanical medicine or phytomedicine refers to using a plant’s seeds, berries, roots, leaves, bark, or flowers for medicinal purposes. Herbalism has a long tradition of use outside of conventional medicine. It is becoming more mainstream as improvements in analysis and quality control along with advances in clinical research show the value of herbal medicine in the treating and preventing disease.

Traditional herbal medicines are naturally occurring, plant-derived substances with minimal or no industrial processing that have been used to treat illness within local or regional healing practices.
In consumption market, Europe and Asia Pacific are the mainly consumption regions due to the bigger demand of downstream applications. In 2017, these two regions occupied 72.36% of the global consumption volume in total.

Market Analysis and Insights: Global Herbal Medicine Market
The global Herbal Medicine market size is projected to reach USD 218940 million by 2026, from USD 148360 million in 2020, at a CAGR of 6.7% during 2021-2026.

This report classifies the global Herbal Medicine industry breakdown information by manufacturers, region, type and application. Additionally, studies the market status, share, rate of growth, future trends, market drivers, opportunities and challenges, risks and entry barriers, sales channels, distributors and Porter’s 5 Forces Analysis of Herbal Medicine Market.

Herbal Medicine research report has combined the analysis of different aspects that increase the market’s growth. It constitutes trends, restraints, and drivers that transform the market in either a positive or negative manner. This report also provides the scope of different segments and applications that can potentially influence the market in the future.

To Understand How COVID-19 Impact is Covered in this Herbal Medicine Report Click Here…

Market Segmentation Analysis: The Herbal Medicine research report includes specific segments by region (country), by manufacturers, by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. by Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the Herbal Medicine market growth.

By Company:

● Tsumura ● Schwabe ● Madaus ● Weleda ● Blackmores ● Arkopharma ● SIDO MUNCUL ● Arizona Natural

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The role of herbal medicine in diabetes treatment.

Opinions of Saturday, 14 November 2020

Columnist: Cephas Kwaku Debrah


The writer is a Teaching Assistant at the Department of Herbal Medicine, KNUSTThe writer is a Teaching Assistant at the Department of Herbal Medicine, KNUST

World Diabetes Day was coined by the World Health Organization (WHO) and the International Diabetes Federation (IDF) in 2006. It has since been celebrated every year on November 14th.

Its purpose has been to promote the need to take coordinated and concerted actions to confront diabetes as a critical global health issue.

Diabetes has now become one of the world’s leading non-communicable diseases that affect the body’s ability to make or use insulin.

There are three main types of diabetes – type 1, type 2 and gestational. The body’s blood sugar levels are remarkably constant and rarely outside the range of 3.5?8.0 mmol/L but if an individual record continues fasting blood sugar over 8 mmo1/L or a random value over 11.1 mmo1/L the person is said to be diabetic.

Common symptoms include frequent urination, fatigue, weight loss, slow wound healing, blurry vision and frequent infections. Diabetes if left untreated may lead to nerve, kidney and eye damage, hearing impairment, foot gangrene, miscarriages, stroke and Alzheimer disease among others.

Significant number of Ghanaians are known to suffer from this disorder with the prevalence increasing with age and being higher in urban than in rural areas. Most patients often struggle to make the necessary lifestyle changes to control blood sugar levels, and most current medications have also been known to have some unfavorable adverse effects.

Role of Herbal medicines

Herbal medicines have over the years played an important role in the management of diabetes and its related complications. Clinical studies and various researches have proven the effectiveness of some medicinal plants and herbal formulations in the management of the disease.

Typical among them include: Charantia mormodica – Bitter melon (Asante twi: Nyanya), Ageratum conyzoides- Goat weed (Asante twi: Guakuro), Azadirachta indica -Neem (Asante twi: Dua Gyane), Bridelia micrantha- Bridelia (Asante twi: Opam fufuo), Hymenocardia acida- Heart fruit (Asante twi: Duakokowa), Morinda lucida – Brimstone tree (Asante twi: Bronyadua Konkroma), Moringa oleifera -Drumstick Tree (Ewe: Babatsi) and Tetrapleura tetraptera- Aidan fruit (Asante twi: Prekese).

The anti-hyperglycemic effects that result from treatment with some of these plants is often due to its ability to improve the performance of pancreatic tissue, which is achieved by increasing insulin secretions or reducing the intestinal absorption of glucose.

Research suggests that medicinal plants do not only promote normal blood sugar levels (normoglycaemia) but are also effective for the management of other conditions and complication associated with it.

Medicinal plants like Baphia nitida -African sandalwood (Asante twi: Odwen) and Spathodea campanulata –African tuliptree (Asante twi: Kokoanisuo) are recommended for the management of diabetic wound, Morinda lucida – Brimstone tree (Asante twi: Bronyadua Konkroma) for diabetic retinopathy, Terminalia catapa –Indian almond (Asante twi: Abrofo nkate?) for diabetic nephropathy with amnesia and Theobroma cacao –Cocoa (Asante twi: Kookoo) for diabetic neuropathy.

As we celebrate World Diabetes Day to promote the importance of taking coordinated and concerted actions

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Kano arrests 30 herbal medicine hawkers for use of vulgar languages

#EndSARS: Police commend Kano youths for peaceful conduct

By Bashir Bello, Kano

Not fewer than 30 hawkers of herbal medicines were arrested by the Kano State government for using vulgar languages to advertise their products in the state.

These practitioners go about on the major streets and market places using loudspeakers to advertise their products to their respective customers.

The exercise leading to the arrest of the hawkers was spearheaded by the Private Health Institutions Management Agency, PHIMA.

The Agency’s Executive Secretary, Usman Tijjani Aliyu said the task force also impounded 30 cars and wheelbarrows used by the culprits.

Aliyu said, “the task force was established by the Kano State Ministry of Health and my agency (Private Health Institutions Management Agency, PHIMA) was given the mandate to carry out the exercise.

“As at yesterday, Sunday, we have arrested 30 culprits for using vulgar languages to advertise their products. During the first exercise, we arrested 13 and now we arrested another 17 of them. The exercise continues.

“We also impounded thirty cars and wheelbarrows used by the culprits.

“The task force is mandated to sanitize the activities of persons who go to the streets and market places to use loudspeakers and vulgar languages to advertise their products. And the exercise is ongoing.

“They were apprehended around Gyadi-gyadi/Court road, ‘Yan kaba bus stop, Janguza market, Kofar ruwa, Katsina road, ‘Yan kura and Bata.

“The Private Health institutions management agency Taskforce is on a rampage to liberate the people of Kano state from the menace of rampant hawking of Traditional medicines using vulgar words.

“The agency would like to express its appreciation and gratitude to the good people of Kano for their support and information they have been providing continuously to the Taskforce,” Aliyu however stated.

The task force has a backup of security operatives which comprises the police, NSCDC, Hisbah among others.


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UH professor is developing a Chinese herbal medicine formula to improve cancer therapy

University of Houston professor of pharmaceutics Ming Hu is developing and testing an ancient Chinese herbal medicine formula, first described in 280 A.D., to improve cancer therapy. Hu believes Xiao-Chai-Hu Tang (XCHT) can protect people on the chemotherapy drug Irinotecan from a deadly side effect: Severe-delayed-onset diarrhea (SDOD).

The clinical use of Irinotecan is severely limited by the severe diarrhea that results in poor quality of life, hospitalization and even death. Our goal with XCHT is to allow more people to benefit from the treatment by Irinotecan, which is often the drug of last resort for late stage or metastatic cancer patients.”

Ming Hu, the Diana S-L. Chow Endowed Professor of Drug Discovery and Development at UH

Hu and colleagues Romi Ghose, associate professor of pharmaceutics at UH and Song Gao of Texas Southern University, have been awarded $996,162 from the National Cancer Institute to investigate the effectiveness of the ancient formula. They will also work with Lijun Zhu of Guangzhou University of Chinese Medicine in China to determine the agent’s effectiveness in a clinical trial.

To be sure, Irinotecan is a powerful weapon against cancer, but many of those who take it develop SDOD, likely caused by SN-38, the active metabolite of the drug. In the intestine, SN-38 can damage intestinal cells and affect their renewal.

“Intestinal cells have UGT enzymes that detoxify SN-38, but we found that SN-38 can also inactivate and reduce UGT enzymes in the intestine. This creates a vicious cycle. Approximately 1-in-5 patients will fall into this vicious cycle, leading to discontinuation of therapy, decreased efficacy or even death,” said Hu. He has shown that XCHT protects the UGT enzymes and reduces severe diarrhea, and with the new grant he will develop it further, for testing and approvals.

XCHT is actively used in China, Japan and Korea for liver protection. This is the first instance where it has been shown to protect the intestine from SN-38, making the UGT enzymes more resistant to the impact of SN-38.

“Our long-term goal is to develop experimental therapeutics and/or nutritional supplemental approaches to reduce SDOD, so patients can sustain their chemotherapy,” said Hu.

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Global Herbal medicine market size to exceed USD 411 billion by 2026

The latest report on ‘herbal medicine market’ thoroughly scrutinizes this business space while providing qualitative insights, historical data, and verifiable projections for 2020-2026 to the companies that are operational in this industry.

Selbyville, Delaware, Oct. 29, 2020 (GLOBE NEWSWIRE) — According to the credible sources, global herbal medicine market is expected to reach a valuation of USD 411.2 billion by the year 2026. Increasing product adoption by the population across the world, rising support & funding from government for research & development of herbal medicines, and easy availability of the product are the major factors propelling the industry growth. Further, benefits such as low cost, and no side effects are also contributing to herbal medicine market outlook.

Global herbal medicine market report studies the landscape based on several segmentations, such as source type, distribution channel, category, form, and regional outlook. It enlists the factors that influence the segmental share along with their growth rate projections over the analysis timeframe. Furthermore, the document contains granular information about competitive landscape of the market defined by each participant, along with their business profile, product portfolio, and market stake.

Highlighting category

Estimates cites that herbal pharmaceuticals segment held a major share in global herbal medicine industry in 2019, owing to rising geriatric population, and high consumer awareness. Other factors like negligible side effects, supplier innovations, and launch of Current Good Manufacturing Practices (CGMP) by the FDA for dietary supplements are expected to drive the segmental growth.

Meanwhile, herbal beauty products segment is predicted to register robust growth rate during the forecast period, mainly due to increase in sales of beauty products. High disposable income, and availability of large product portfolio are stimulating the overall market remuneration.

Request Sample copy of this Report @ https://www.marketstudyreport.com/request-a-sample/2963796/

Elaborating form outlook

Global herbal medicine market, as per form type, is segmented into powders, tablets & capsules, syrups, extracts, and others. Among these, extract segment is expected to witness high gains during the forecast period, owing to its utilization in manufacturing several products. Herbs & plants extracts vary from alcoholic extracts, hot water extracts to long-term boiled extracts, and acetic acid extracts depending on the solvent.

Considering source type

As per the report, whole plant sourced herbal medicine market segment is gaining substantial traction due to product’s ability to cure various diseases. As per National Center for Biotechnology Information, about 70% to 80% of the population worldwide preferred traditional drugs for treatment.

Notably, traditional medications are extracted from roots & barks, leaves, fruits, flowers, stalk, and cloves of the plant. For instance, chamomile, a flower, is used as sedative and anxiolytic for relaxation and anxiety. It also reduces swelling and inflammation while aiding in wound healing.  

Analyzing distribution channel

Worldwide herbal medicine market share from e-commerce segment is projected to grow momentously during the forecast period, owing to rising awareness regarding traditional medication, high penetration of mobile phones with internet facilities, and easy accessibility in small towns & villages. Further, rising geriatric population, and cost efficiency of

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