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dentist

OKC Dentist Working With On-Site Lab to Bring Patients Best in Cosmetic Dentistry

OKLAHOMA CITY, Dec. 2, 2020 /PRNewswire-PRWeb/ — Providing the highest quality, longest lasting and most honest dentistry available has been a commitment of OKC dentist Dr. Chris Saxon’s since he began practicing dentistry. He is keeping this commitment by providing his patients with an on-site dental lab. This allows Dr. Saxon and his team at Saxon Dentistry to work hand in hand with the lab specialists to ensure an outstanding level of quality and service.

The Saxon Dentistry Difference

In most practices, the standard procedure is to outsource your dental lab needs. These typically include dentures, dental crowns, porcelain veneers, implant restorations and more. While convenient and often less expensive for dentists, quality and precision are often compromised. With Saxon Dentistry, this is kept on-site, ensuring greater quality control, accuracy of fit and most importantly, higher patient satisfaction.

When patients embark on full smile makeovers, dental implants, porcelain veneers and even a single crown, they are putting a lot of trust in their dentist. This trust is not taken lightly at Saxon Dentistry. The on-site lab utilizes top tier dental materials, advanced technology and employs skilled, meticulous technicians. Combining this with Dr. Saxon’s expertise allows for predictable, high quality outcomes.

When teaming up with the on-site dental lab specialist, Dr. Saxon can bring them directly into the room with the patient and together listen to the patient’s concerns. Without an on-site lab, dentists have to relay information to their labs via phone call or email. Details get lost in translation, and details matter greatly when customizing a smile for patients. Sometimes the most minor adjustment can have the biggest impact.

Smile Makeovers OKC

Dr. Saxon has a particular passion for making dentistry beautiful and natural. His keen eye for detail can make any dental restoration, from a single cracked tooth repair to dental veneers to full mouth dental implants, blend seamlessly into a smile. This has made him a highly sought after OKC cosmetic dentist and implant dentist.

“When dentistry is done to the highest level, no one should be able to detect that you’ve had dental work completed.”

He believes in meeting patients exactly where they are in life, understanding their goals and setting forth the appropriate treatment from there. There is no one size fits all dentistry in his office. Personalized care is not only necessary; it’s what every patient deserves that walks through a dentist’s door.

Get to Know Oklahoma City Native, Dr. Chris Saxon

Dr. Saxon is a native of Oklahoma City and a graduate of Putnam City North high school. He received his doctorate from the University of Oklahoma College Of Dentistry. He takes between 100-150 hours of continuing education every year, far exceeding the Oklahoma Board of Dentistry’s requirements.

Dr. Saxon is committed to giving back to the local community. One way he does this is by being an Oklahoma Mission of Mercy participant. Dr. Saxon is an avid golfer, cyclist and kite boarder, but his greatest joy comes from spending time with

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medicine

UCLA Health collaborates with Regeneron Genetics Center to bring genomic medicine to patients

UCLA Health has entered into a collaborative research agreement with the Regeneron Genetics Center (RGC) to provide whole exome sequencing for 150,000 UCLA Health patients. Led by the UCLA Institute for Precision Health (IPH), this initiative is set to become one of the largest and most comprehensive in the nation and is a key step in bringing genomic medicine to patients across California.

We’ve talked for some time about the promise of precision medicine – a time when preventive measures and targeted treatments can be individualized to each patient’s genetic makeup. This is a watershed moment in that timeline, a big step toward that reality and a turning point in our research dedicated to changing the way future health care will be delivered for our patients and our community.”


Dr. Daniel Geschwind, Gordon and Virginia MacDonald distinguished professor, senior associate dean and associate vice chancellor of Precision Health

The new exome-sequencing collaboration builds on genotyping work underway with the UCLA ATLAS Community Health Initiative – a large collection of diverse patient blood, saliva and tissue samples being analyzed to help UCLA researchers and clinicians develop and deliver the best care possible. Genotyping, which is targeted to a specific place in the DNA, looks for a predefined set of variants, but whole exome sequencing – like that being performed through the new RGC collaboration – analyzes thousands of protein-coding genes and can provide information on many more potential mutations. Using a needle and haystack analogy, genotyping looks for predetermined needles in a specific location, while exome sequencing searches more of the haystack to detect unexpected needles.

“All patients who participate in this research will be given the opportunity to opt in or out of having actionable results – those that could directly impact their clinical care – returned to them. All patient information and specimens used in the research are ‘de-identified’ to protect patient privacy and confidentiality. Actionable results, which are verified by a UCLA CLIA-certified laboratory, are only returned to those patients who specifically say they want them,” Dr. Geschwind said, adding that about 2% to 3% of tested patients are expected to have a result that will have immediate clinical implications.

The RGC, a wholly owned subsidiary of the science-focused biotechnology company Regeneron, has built one of the world’s largest genetics databases, pairing the sequenced exomes and de-identified electronic health records of more than 1 million people, through collaborations with nearly 100 global health care and academic institutions. Building upon Regeneron’s strengths in genetics-driven drug discovery, the information secured from this initiative will allow for the elucidation, on a large scale, of genetic factors that cause or influence a range of human diseases.

Three factors make this research effort particularly strong: the depth of UCLA Health’s patient care and research expertise; the ethnic diversity of Los Angeles and the Southern California region; and RGC’s leading genetics research, sequencing and analysis capabilities.

“Including diverse populations is critical to

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fitness

COVID-19: Health officials bring in new orders in two health regions, including no social gatherings

Article content continued

Health officials also say travel must be limited to essential travel only in the Fraser Health and Vancouver Coastal health regions.

Henry said B.C. is seeing “dangerously high and rapid increases” in COVID-19 cases, and said the next two weeks are critical.

The next news conference and COVID-19 update will be Monday at 3 p.m.

On Friday, they reported 589 new cases, the highest number in one day for the province, and two more deaths, which means 275 people in B.C. have died from the virus.

Of the 589 cases, 104 people are in hospital with COVID-19, including 28 in intensive care. The remaining people with COVID-19 are recovering at home in self-isolation.

Health officials also announced there have been six new health-care facility outbreaks at Suncreek Village, Fort Langley Seniors Community, Northcrest Care Centre, Fellburn Care Center – PATH unit, Ridge Meadows Hospital and Langley Memorial Hospital.

In total, 31 long-term care or assisted-living facilities and four acute-care facilities have active outbreaks.

In a grim joint statement, Henry and Dix alluded to “the gathering storm clouds of increased exposures and transmission,” and encouraged businesses, particularly in the Lower Mainland, to review their COVID-19 safety plans.

“As we have done with many sectors, public health teams are continually reviewing guidance and working with individual business owners to help navigate the challenges of COVID-19 and continue to operate safely,” said Henry.

“When faced with the gathering storm clouds of increased exposures and transmission in a particular sector, we step up inspections to identify gaps and, at times, increase the safety measures that are required. Only if it is clearly demonstrated that a business or sector is unable to operate safely are businesses ordered to close.”

More to come…

Source Article

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medicine

Igentify, Genosity cooperate to bring precision medicine to all markets

Israeli digital health company Igentify will cooperate with US-based biotech firm Genosity to deliver the next step in precision medicine to all markets. Precision medicine is a new trend in the healthcare industry, Igentify director of partnerships Yael Furman told The Jerusalem Post.  

“Imagine a person suffering from a headache,” she said, “that person would take an aspirin. The drug is produced for all people who suffer from a headache. Yet in some cases, such as cancer, it’s extremely useful to know the genetic profile of the patient as that would make the treatment a lot more effective.” 

This still means mass-produced drugs for the most common genetic types in a given population, but perhaps drugs will eventually be made for the unique individual who needs them.  

The trend is coupled with other leaps and bounds medicine is going through thanks to big data and the digital age. For example, a woman who has a genetic likelihood to suffer from breast cancer could get digital “pushes” in the form of texts and emails that will remind her to get tested. Better and more frequent testing saves lives.  

“People see our animated videos and forget the mountain of work that goes into genetic research,” Igentify founder and CEO Dr. Doron Behar explains.  

“The videos are important because we want people to understand what the genetic test is, what will happen to their data, and to give their informed consent. Yet that is just the last step – what we do much more,” he said.

“There are only 7,000 genetic counselors in the world today,” Behar said. “This is a huge bottle neck that prevents people from having access to, and benefiting from, their own genetic data. Machine learning can take some of that burden off and deliver the service to more [people]. ”   

IGENTIFY HELPS medical service providers to set up the complex systems needed to decipher such data – from cheek swabs to lab robots to machine learning that is able to scan most possibilities of human genetic material creating a new life.   

“We use cheek swabs because they’re easier to do than blood samples and give us cells from the human cheek,” he explains, “it’s not the spit we’re after, it’s cells. Each cell has your entire genome in it.”  

If a man and a woman are thinking about having a baby together and if they have access to a genetic testing service, it could predict what is the likelihood of the yet-unborn child having a genetic disease based on the genetic analysis of both parents.  

A woman could use a simple cheek swab to learn if she is at risk of suffering from breast cancer. The information is presented in a friendly and easy to understand animated video that has a lot of planning behind it.   

“We’re able to offer this service not just in other languages but also with different avatars,” Behar pointed

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health

NeoLight’s jaundice treatment catches another $7 million to bring neonatal light therapy to the home

The Daily Beast

White House Press Secretary Kayleigh McEnany Is Now Formally Moonlighting as a Trump Campaign Aide

White House press secretary Kayleigh McEnany appears to have taken on a new gig. In addition to her role as a government employee, she’s now serving as a senior aide on her boss’s reelection campaign.In an appearance on Fox News on Tuesday morning, McEnany was introduced as “Trump 2020 senior advisor and White House press secretary.” A few hours later, Fox Business Network host Stuart Varney introduced McEnany by saying she is “serving now as advisor for the Trump campaign.”McEnany’s dual roles for the White House and the Trump reelection campaign immediately set off alarm bells among good government advocates, who said they represent yet another instance of the often blurry lines between the Trump administration and the president’s political operation.“This looks like the latest example of Trump administration officials bending and breaking ethics laws and norms,” said Paul Seamus Ryan, the vice president of litigation for the group Common Cause. “This is unfortunately par for the course for this administration.”Now Kayleigh McEnany Has COVID, Making a Dozen From Rose Garden CeremonyA White House spokesperson said McEnany was not representing the White House during her Fox appearances on Tuesday.“Kayleigh was appearing in her personal capacity as a private citizen,” the spokesperson said.A spokesperson for the Trump campaign confirmed that McEnany is an unpaid advisor, and also said she was appearing on Fox on Tuesday in a personal capacity. The spokesperson said that cable news shows on which she appears “have been instructed not to refer to her with her White House title,” notwithstanding the Fox & Friends introduction on Tuesday that included both her campaign and White House titles.While most of McEnany’s two Fox hits on Tuesday concerned the status of the Trump campaign and the 2020 race, she also weighed in on official administration policy on issues such as COVID relief negotiations with congressional Democrats.“The chances [for a deal] are slim when you have someone like Nancy Pelosi as Speaker of the House,” McEnany told Varney. “If we’re providing stimulus relief for the American people, it should be just that, for American people, for United States citizens, not a wish-list from the liberal left,” McEnany told Varney.Speaking in front of a backdrop that featured both the White House and the Trump campaign logo, McEnany also rattled off a series of policy proposals that “we offered” in those negotiations.Fox News Reporter Explodes Over Kayleigh McEnany: ‘Stop Blaming the Media, I’m Tired of It!’It’s that sort of blurry line between White House and campaign messaging, and the prospect that taxpayer resources could continue bolstering the president’s reelection effort, that concerns Ryan.“This excerpt is McEnany commenting on federal government policy currently being negotiated by the Trump administration with Congress. This is McEnany doing the work of a [White House] Press Secretary,” he said. “It’s permissible for someone who works in the White House to also do campaign work. They just can’t mix the two.

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health

Helping Alzheimer’s Patients Bring Back Memories

People of all ages have moments when it feels like we’re on the edge of recalling something but can’t quite do it—where we parked our car or left our phone, for example, or what name goes with that familiar face. It’s extremely frustrating in the moment, but for most of us, we can usually remember if we try. For patients with Alzheimer’s, Huntington’s and many other dementia-causing diseases, however, memory loss is much more profound.

Given the steady rise in the numbers of Alzheimer’s patients, in particular, the research community and pharmaceutical companies agree that the development of treatment strategies is critical, now more than ever. Yet despite decades of research, we are still trying to understand why these patients can’t remember—and trying to find some way we might be able to help.

But we may be closer to an answer.

A well-known feature of early Alzheimer’s is a difficulty remembering recent events. We’ve always assumed that there are two possible explanations: one is that these patients can’t store new information properly in the brain; the other is that their ability to recall stored information has been weakened. But maybe there’s another way to think about it. Consider a public library in which each book represents a memory. If the library doesn’t have the book you want, you’re out of luck. This would be like asking Alzheimer’s patients to remember something that hasn’t been stored in their brain in the first place.

Even if the library has the book, though, you still need several pieces of information to locate it—what floor it’s on, what rack, what row on the rack. If you were missing some of that information, you wouldn’t find it either. That corresponds to the second assumption about why people with Alzheimer’s can’t remember. Although most research has focused on ways of improving memory storage in Alzheimer’s, this has not led to led to treatments capable of improving recall.

On the other hand, scientific evidence in support of the “weakened memory recall” idea in Alzheimer’s has been difficult to obtain, which is why this possibility has received considerably less attention. But in a Nature paper published in 2016, our team investigated both memory storage and memory recall processes in an animal model of early Alzheimer’s disease. In clinical research, there is no simple method to distinguish between memory storage versus recall deficits in Alzheimer’s patients, because standard cognitive tests rely on the patient’s ability to verbally describe previous events.

To circumvent this issue, I developed an approach that allowed us to activate the neurons that store memory information, referred to as memory engrams, through optogenetics—that is, introducing a gene that is light sensitive into the memory engram cells of “Alzheimer’s” mice, then delivering blue light pulses to activate them—and measuring memory recall strength directly. To our surprise, we found comparable numbers of engram cells in normal healthy animals and Alzheimer’s animals, suggesting that the initial memory storage process is intact. Targeting the recall process in Alzheimer’s animals led

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